The AACR Project GENIE® Registry is a continuously evolving, publicly available real-world data resource, housing:
- 289,000+ clinical-grade genomic samples from 242,000+ patients
- ~30,000 new patients added annually
- High-fidelity clinico-genomic data from academic tertiary referral centers
- International representation (U.S. and ex-U.S. patient populations)
Why It Matters
The breadth and quality of AACR Project GENIE® data support a broad range of precision oncology research applications, including:
- Biomarker Discovery: Identifying and validating predictive biomarkers.
- Clinical Trial Feasibility: Informing trial design and patient selection.
- Regulatory-Grade RWD: Supporting real-world evidence (RWE) submissions.
Unlike commercial datasets primarily sourced from community practices, the AACR Project GENIE® Registry reflects real-world clinical practice at leading academic cancer centers, ensuring data quality, diversity, and regulatory relevance.