AACR Project GENIE® (Genomics Evidence Neoplasia Information Exchange, GENIE) is a nonprofit, contract research organization (CRO) wholly owned by the AACR, that powers a unique research platform.
We collaborate with research leaders across the oncology ecosystem to unlock innovation across the entire oncology R&D lifecyle – from target discovery and trial design to post-market regulatory activities – delivering best-in-class real-world data (RWD) solutions.
GENIE is powered by two tightly integrated assets:
| Core Asset | What It Is | Why It Matters |
| The GENIE Registry | The world’s largest open-access, pan-cancer clinico-genomic real-world data repository (250,000+ tumors and growing). | Delivers deeply curated, longitudinal molecular & outcomes data suitable for exploratory science and regulatory-grade evidence. |
| The GENIE Consortium | A legally-bound network of 20 premier academic cancer centers across North America, Europe, and Asia. | Provides prospective data feeds, fit-for-purpose biospecimens, and turnkey infrastructure for multi-site studies, ensuring speed, quality, and global representativeness. |
Together, the Registry and Consortium form a scalable oncology RWD ecosystem that empowers every stakeholder to accelerate precision medicine innovation.